The relevance of PTEN-AKT in relation to NOTCH1-directed treatment strategies in T-cell acute lymphoblastic leukemia. [electronic resource]
Producer: 20170707Description: 1010-7 p. digitalISSN:- 1592-8721
- Amyloid Precursor Protein Secretases -- antagonists & inhibitors
- Animals
- Antineoplastic Agents -- therapeutic use
- Drug Resistance, Neoplasm -- genetics
- Gene Expression Regulation, Leukemic -- drug effects
- Humans
- Molecular Targeted Therapy
- Mutation
- PTEN Phosphohydrolase -- genetics
- Precursor T-Cell Lymphoblastic Leukemia-Lymphoma -- drug therapy
- Proto-Oncogene Proteins c-akt -- genetics
- Receptor, Notch1 -- genetics
- Signal Transduction -- drug effects
- Tumor Suppressor Proteins -- genetics
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Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't
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