Histone H3K27 Trimethylation Modulates 5-Fluorouracil Resistance by Inhibiting PU.1 Binding to the DPYD Promoter. [electronic resource]
Producer: 20170811Description: 6362-6373 p. digitalISSN:- 1538-7445
- Dihydrouracil Dehydrogenase (NADP) -- genetics
- Drug Resistance, Neoplasm
- Enhancer of Zeste Homolog 2 Protein -- physiology
- Fluorouracil -- pharmacology
- Histones -- metabolism
- Humans
- Methylation
- Promoter Regions, Genetic
- Proto-Oncogene Proteins -- antagonists & inhibitors
- Trans-Activators -- antagonists & inhibitors
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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