Adrenomedullin blockade suppresses sunitinib-resistant renal cell carcinoma growth by targeting the ERK/MAPK pathway. [electronic resource]
Producer: 20180315Description: 63374-63387 p. digitalISSN:- 1949-2553
- Adrenomedullin -- antagonists & inhibitors
- Animals
- Apoptosis -- drug effects
- Biomarkers, Tumor -- genetics
- Carcinoma, Renal Cell -- drug therapy
- Cell Proliferation -- drug effects
- Drug Resistance, Neoplasm
- Extracellular Signal-Regulated MAP Kinases -- antagonists & inhibitors
- Humans
- Indoles -- pharmacology
- Kidney Neoplasms -- drug therapy
- MAP Kinase Signaling System -- drug effects
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Prognosis
- Pyrroles -- pharmacology
- Sunitinib
- Survival Rate
- Tumor Cells, Cultured
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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