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  2. Details for: Discovery of Imidazoquinolines as a Novel Class of Potent, Selective, and in Vivo Efficacious Cancer Osaka Thyroid (COT) Kinase Inhibitors.
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Discovery of Imidazoquinolines as a Novel Class of Potent, Selective, and in Vivo Efficacious Cancer Osaka Thyroid (COT) Kinase Inhibitors. [electronic resource]

By:
  • Glatthar, Ralf
Contributor(s):
  • Stojanovic, Aleksandar
  • Troxler, Thomas
  • Mattes, Henri
  • Möbitz, Henrik
  • Beerli, Rene
  • Blanz, Joachim
  • Gassmann, Ernst
  • Drückes, Peter
  • Fendrich, Gabriele
  • Gutmann, Sascha
  • Martiny-Baron, Georg
  • Spence, Fiona
  • Hornfeld, Jeff
  • Peel, John Edmonson
  • Sparrer, Helmut
Producer: 20170606Description: 7544-60 p. digitalISSN:
  • 1520-4804
Subject(s):
  • Animals
  • Crystallography, X-Ray
  • Dogs
  • Dose-Response Relationship, Drug
  • Drug Discovery
  • Humans
  • Imidazoles -- chemical synthesis
  • MAP Kinase Kinase Kinases -- antagonists & inhibitors
  • Male
  • Models, Molecular
  • Molecular Structure
  • Protein Kinase Inhibitors -- chemical synthesis
  • Proto-Oncogene Proteins -- antagonists & inhibitors
  • Quinolines -- chemical synthesis
  • Rats
  • Rats, Sprague-Dawley
  • Structure-Activity Relationship
  • Tumor Necrosis Factor-alpha -- antagonists & inhibitors
Online resources:
  • Available from publisher's website
In: Journal of medicinal chemistry vol. 59
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Publication Type: Journal Article

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Discovery of Imidazoquinolines as a Novel Class of Potent, Selective, and in Vivo Efficacious Cancer Osaka Thyroid (COT) Kinase Inhibitors.

APA

Glatthar R., Stojanovic A., Troxler T., Mattes H., Möbitz H., Beerli R., Blanz J., Gassmann E., Drückes P., Fendrich G., Gutmann S., Martiny-Baron G., Spence F., Hornfeld J., Peel J. E. & Sparrer H. (20170606). Discovery of Imidazoquinolines as a Novel Class of Potent, Selective, and in Vivo Efficacious Cancer Osaka Thyroid (COT) Kinase Inhibitors. : Journal of medicinal chemistry.

Chicago

Glatthar Ralf, Stojanovic Aleksandar, Troxler Thomas, Mattes Henri, Möbitz Henrik, Beerli Rene, Blanz Joachim, Gassmann Ernst, Drückes Peter, Fendrich Gabriele, Gutmann Sascha, Martiny-Baron Georg, Spence Fiona, Hornfeld Jeff, Peel John Edmonson and Sparrer Helmut. 20170606. Discovery of Imidazoquinolines as a Novel Class of Potent, Selective, and in Vivo Efficacious Cancer Osaka Thyroid (COT) Kinase Inhibitors. : Journal of medicinal chemistry.

Harvard

Glatthar R., Stojanovic A., Troxler T., Mattes H., Möbitz H., Beerli R., Blanz J., Gassmann E., Drückes P., Fendrich G., Gutmann S., Martiny-Baron G., Spence F., Hornfeld J., Peel J. E. and Sparrer H. (20170606). Discovery of Imidazoquinolines as a Novel Class of Potent, Selective, and in Vivo Efficacious Cancer Osaka Thyroid (COT) Kinase Inhibitors. : Journal of medicinal chemistry.

MLA

Glatthar Ralf, Stojanovic Aleksandar, Troxler Thomas, Mattes Henri, Möbitz Henrik, Beerli Rene, Blanz Joachim, Gassmann Ernst, Drückes Peter, Fendrich Gabriele, Gutmann Sascha, Martiny-Baron Georg, Spence Fiona, Hornfeld Jeff, Peel John Edmonson and Sparrer Helmut. Discovery of Imidazoquinolines as a Novel Class of Potent, Selective, and in Vivo Efficacious Cancer Osaka Thyroid (COT) Kinase Inhibitors. : Journal of medicinal chemistry. 20170606.

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