Peperomin E reactivates silenced tumor suppressor genes in lung cancer cells by inhibition of DNA methyltransferase. [electronic resource]
Producer: 20170206Description: 1506-1519 p. digitalISSN:- 1349-7006
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Benzodioxoles -- chemistry
- Cell Line, Tumor
- Cell Survival -- drug effects
- DNA (Cytosine-5-)-Methyltransferases -- antagonists & inhibitors
- DNA Methylation
- Disease Models, Animal
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Gene Silencing
- Genes, Tumor Suppressor
- Humans
- Lung Neoplasms -- genetics
- Mice
- Models, Molecular
- Molecular Conformation
- Protein Binding
- Structure-Activity Relationship
- Transcriptional Activation -- drug effects
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Publication Type: Journal Article
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