Minnelide/Triptolide Impairs Mitochondrial Function by Regulating SIRT3 in P53-Dependent Manner in Non-Small Cell Lung Cancer. [electronic resource]
Producer: 20170808Description: e0160783 p. digitalISSN:- 1932-6203
- Acetylation
- Antineoplastic Agents, Alkylating -- pharmacology
- Apoptosis -- drug effects
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Diterpenes -- pharmacology
- Epoxy Compounds -- pharmacology
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Lung Neoplasms -- drug therapy
- Membrane Potential, Mitochondrial -- drug effects
- Mitochondria -- drug effects
- Organophosphates -- pharmacology
- Oxidative Stress -- drug effects
- Phenanthrenes -- pharmacology
- RNA, Small Interfering -- genetics
- Reactive Oxygen Species -- metabolism
- Sirtuin 3 -- antagonists & inhibitors
- Tumor Cells, Cultured
- Tumor Suppressor Protein p53 -- antagonists & inhibitors
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Publication Type: Journal Article
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