The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. [electronic resource]
Producer: 20160922Description: 594-8 p. digitalISSN:- 1095-9203
- Antineoplastic Agents -- chemistry
- Biocatalysis -- drug effects
- Boron Compounds -- chemistry
- Boronic Acids -- chemistry
- Bortezomib -- chemistry
- Catalytic Domain -- drug effects
- Crystallography, X-Ray
- Drug Design
- Glycine -- analogs & derivatives
- Humans
- Proteasome Endopeptidase Complex -- chemistry
- Proteasome Inhibitors -- chemistry
- Protein Conformation
- Threonine -- analogs & derivatives
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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