Chemotherapy resistance and metastasis-promoting effects of thyroid hormone in hepatocarcinoma cells are mediated by suppression of FoxO1 and Bim pathway. [electronic resource]
Producer: 20170929Description: e2324 p. digitalISSN:- 2041-4889
- Animals
- Apoptosis -- drug effects
- Base Sequence
- Bcl-2-Like Protein 11 -- genetics
- Carcinoma, Hepatocellular -- genetics
- Cisplatin -- pharmacology
- Down-Regulation -- drug effects
- Doxorubicin -- pharmacology
- Drug Resistance, Neoplasm -- drug effects
- Forkhead Box Protein O1 -- metabolism
- Gene Expression Regulation, Neoplastic -- drug effects
- Hep G2 Cells
- Humans
- Liver Neoplasms -- genetics
- Mice, Inbred BALB C
- Mice, Nude
- Neoplasm Metastasis
- Promoter Regions, Genetic -- genetics
- RNA, Messenger -- genetics
- Receptors, Thyroid Hormone -- metabolism
- Signal Transduction -- drug effects
- TNF-Related Apoptosis-Inducing Ligand -- pharmacology
- Thyroid Hormones -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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