Aromatic heterocyclic esters of podophyllotoxin exert anti-MDR activity in human leukemia K562/ADR cells via ROS/MAPK signaling pathways. [electronic resource]
Producer: 20170213Description: 226-235 p. digitalISSN:- 1768-3254
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- metabolism
- Antineoplastic Agents -- chemistry
- Cell Cycle Checkpoints -- drug effects
- Drug Resistance, Multiple -- drug effects
- Esters -- chemistry
- Gene Expression Regulation, Neoplastic -- drug effects
- Heterocyclic Compounds -- chemistry
- Humans
- K562 Cells
- MAP Kinase Signaling System -- drug effects
- Podophyllotoxin -- chemistry
- Reactive Oxygen Species -- metabolism
- Structure-Activity Relationship
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Publication Type: Journal Article
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