ω-3 PUFAs ameliorate liver fibrosis and inhibit hepatic stellate cells proliferation and activation by promoting YAP/TAZ degradation. [electronic resource]
Producer: 20180416Description: 30029 p. digitalISSN:- 2045-2322
- Acyltransferases
- Adaptor Proteins, Signal Transducing -- metabolism
- Animals
- Cell Cycle Proteins
- Disease Models, Animal
- Down-Regulation
- Fatty Acids, Omega-3 -- administration & dosage
- Hepatic Stellate Cells -- drug effects
- Liver -- pathology
- Liver Cirrhosis -- drug therapy
- Male
- Mice, Inbred BALB C
- Phosphoproteins -- metabolism
- Proteasome Endopeptidase Complex -- metabolism
- Proteolysis
- Transcription Factors -- metabolism
- Treatment Outcome
- YAP-Signaling Proteins
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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