Adult acute myeloid leukemia with trisomy 11 as the sole abnormality is characterized by the presence of five distinct gene mutations: MLL-PTD, DNMT3A, U2AF1, FLT3-ITD and IDH2. [electronic resource]
Producer: 20180309Description: 2254-2258 p. digitalISSN:- 1476-5551
- Adult
- Aged
- Aged, 80 and over
- Chromosomes, Human, Pair 11
- DNA (Cytosine-5-)-Methyltransferases -- genetics
- DNA Methyltransferase 3A
- Female
- Histone-Lysine N-Methyltransferase -- genetics
- Humans
- Isocitrate Dehydrogenase -- genetics
- Leukemia, Myeloid, Acute -- genetics
- Male
- Middle Aged
- Mutation
- Myeloid-Lymphoid Leukemia Protein -- genetics
- Splicing Factor U2AF -- genetics
- Trisomy
- fms-Like Tyrosine Kinase 3 -- genetics
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Publication Type: Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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