Restoration of R117H CFTR folding and function in human airway cells through combination treatment with VX-809 and VX-770. [electronic resource]
Producer: 20170602Description: L550-9 p. digitalISSN:- 1522-1504
- Aminophenols -- pharmacology
- Aminopyridines -- pharmacology
- Benzodioxoles -- pharmacology
- Cell Line
- Cystic Fibrosis -- drug therapy
- Cystic Fibrosis Transmembrane Conductance Regulator -- genetics
- Drug Evaluation, Preclinical
- Humans
- Mutation, Missense
- Protein Folding -- drug effects
- Quinolones -- pharmacology
- Sequence Deletion
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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