Oral Monomethyl Fumarate Therapy Ameliorates Retinopathy in a Humanized Mouse Model of Sickle Cell Disease. [electronic resource]
Producer: 20170807Description: 921-935 p. digitalISSN:- 1557-7716
- Administration, Oral
- Anemia, Sickle Cell -- blood
- Animals
- Blood-Retinal Barrier -- metabolism
- Carrier Proteins -- genetics
- DNA-Binding Proteins
- Disease Models, Animal
- Electroretinography
- Fumarates -- administration & dosage
- Gene Expression
- Gene Expression Regulation
- Humans
- Intercellular Adhesion Molecule-1 -- genetics
- Mice
- NF-E2-Related Factor 2 -- metabolism
- Neovascularization, Pathologic
- Nuclear Proteins -- genetics
- Oxidative Stress -- drug effects
- Repressor Proteins
- Retina -- drug effects
- Retinal Diseases -- drug therapy
- Retinal Neurons -- drug effects
- Retinal Pigment Epithelium -- drug effects
- Vascular Endothelial Growth Factor A -- genetics
- gamma-Globulins -- genetics
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Publication Type: Journal Article
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