Phase 1 study to evaluate the effect of the MEK inhibitor trametinib on cardiac repolarization in patients with solid tumours. [electronic resource]
Producer: 20170606Description: 491-500 p. digitalISSN:- 1432-0843
- Adolescent
- Adult
- Aged
- Antineoplastic Agents -- administration & dosage
- Area Under Curve
- Cardiotoxicity -- epidemiology
- Electrocardiography
- Electrocardiography, Ambulatory
- Female
- Humans
- MAP Kinase Kinase 1 -- antagonists & inhibitors
- MAP Kinase Kinase 2 -- antagonists & inhibitors
- Male
- Middle Aged
- Models, Biological
- Neoplasms -- drug therapy
- Protein Kinase Inhibitors -- administration & dosage
- Pyridones -- administration & dosage
- Pyrimidinones -- administration & dosage
- Single-Blind Method
- Young Adult
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Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study
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