The combination of trastuzumab and pertuzumab administered at approved doses may delay development of trastuzumab resistance by additively enhancing antibody-dependent cell-mediated cytotoxicity. [electronic resource]
Producer: 20171116Description: 1361-1370 p. digitalISSN:- 1942-0870
- Animals
- Antibodies, Monoclonal, Humanized -- administration & dosage
- Antibody-Dependent Cell Cytotoxicity -- drug effects
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Breast Neoplasms -- immunology
- Cell Line, Tumor
- Drug Resistance, Neoplasm -- drug effects
- Female
- Humans
- Mice
- Mice, SCID
- Receptor, ErbB-2
- Trastuzumab -- administration & dosage
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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