Xanthohumol inhibits the extracellular signal regulated kinase (ERK) signalling pathway and suppresses cell growth of lung adenocarcinoma cells. [electronic resource]
Producer: 20170510Description: 65-73 p. digitalISSN:- 1879-3185
- A549 Cells
- Adenocarcinoma -- drug therapy
- Adenocarcinoma of Lung
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Caspase 3 -- metabolism
- Cell Line, Tumor
- Cyclin D1 -- genetics
- Cyclin-Dependent Kinase Inhibitor p21 -- genetics
- Down-Regulation -- drug effects
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Flavonoids -- pharmacology
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Humans
- Lung Neoplasms -- drug therapy
- MAP Kinase Signaling System -- drug effects
- Propiophenones -- pharmacology
- Signal Transduction -- drug effects
- Tumor Suppressor Protein p53 -- genetics
- Up-Regulation -- drug effects
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Publication Type: Journal Article
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