Gabapentin loses efficacy over time after nerve injury in rats: role of glutamate transporter-1 in the locus coeruleus. [electronic resource]
Producer: 20170306Description: 2024-2032 p. digitalISSN:- 1872-6623
- Amines -- therapeutic use
- Analgesics -- therapeutic use
- Animals
- Antihypertensive Agents -- pharmacology
- Atropine -- pharmacology
- Bronchodilator Agents -- pharmacology
- CREB-Binding Protein -- metabolism
- Clonidine -- pharmacology
- Cyclohexanecarboxylic Acids -- therapeutic use
- Disease Models, Animal
- Excitatory Amino Acid Transporter 2 -- genetics
- Gabapentin
- Locus Coeruleus -- drug effects
- Male
- Norepinephrine -- metabolism
- Pain Threshold -- drug effects
- Peripheral Nerve Injuries -- drug therapy
- RNA, Small Interfering -- pharmacology
- Rats
- Rats, Sprague-Dawley
- Spinal Cord Dorsal Horn -- metabolism
- Time Factors
- gamma-Aminobutyric Acid -- therapeutic use
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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