Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function. [electronic resource]
Producer: 20171010Description: 2637-2650 p. digitalISSN:- 2211-1247
- Animals
- Basic Helix-Loop-Helix Transcription Factors -- metabolism
- Cell Count
- Cell Differentiation
- Embryo, Mammalian -- cytology
- Gene Dosage
- Gene Expression Regulation, Developmental
- Gene Ontology
- Gene Regulatory Networks
- Glucose -- metabolism
- Hepatocyte Nuclear Factor 6 -- metabolism
- Heterozygote
- Homeodomain Proteins -- metabolism
- Homeostasis -- genetics
- Insulin-Secreting Cells -- cytology
- Mice
- Multigene Family
- Nerve Tissue Proteins -- metabolism
- Stem Cells -- cytology
- Trans-Activators -- metabolism
- Weaning
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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