A novel arylbenzofuran induces cervical cancer cell apoptosis and G1/S arrest through ERK-mediated Cdk2/cyclin-A signaling pathway. [electronic resource]
Producer: 20180115Description: 41843-41856 p. digitalISSN:- 1949-2553
- Animals
- Apoptosis -- drug effects
- Benzofurans -- chemistry
- Cell Line, Tumor
- Cyclin A2 -- metabolism
- Cyclin-Dependent Kinase 2 -- metabolism
- Female
- G1 Phase Cell Cycle Checkpoints -- drug effects
- HeLa Cells
- Humans
- Mice, Inbred BALB C
- Mice, Nude
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- metabolism
- Molecular Structure
- Phytotherapy -- methods
- Plant Extracts -- chemistry
- Protein Kinases -- metabolism
- Signal Transduction -- drug effects
- Tumor Burden -- drug effects
- Uterine Cervical Neoplasms -- drug therapy
- Xenograft Model Antitumor Assays -- methods
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Publication Type: Journal Article
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