Chromosome thripsis by DNA double strand break clusters causes enhanced cell lethality, chromosomal translocations and 53BP1-recruitment. [electronic resource]
Producer: 20170605Description: 7673-90 p. digitalISSN:- 1362-4962
- Animals
- CHO Cells
- Cell Death
- Chromosomes, Mammalian -- metabolism
- Chromothripsis
- Clone Cells
- Cricetinae
- Cricetulus
- DNA Breaks, Double-Stranded
- DNA Repair
- Deoxyribonucleases, Type II Site-Specific -- metabolism
- Genome
- Green Fluorescent Proteins -- metabolism
- Metaphase
- Saccharomyces cerevisiae Proteins -- metabolism
- Signal Transduction
- Translocation, Genetic
- Tumor Suppressor p53-Binding Protein 1 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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