Multi-walled carbon nanotubes directly induce epithelial-mesenchymal transition in human bronchial epithelial cells via the TGF-β-mediated Akt/GSK-3β/SNAIL-1 signalling pathway. [electronic resource]
Producer: 20170320Description: 27 p. digitalISSN:- 1743-8977
- Animals
- Bronchi -- drug effects
- Carcinogenicity Tests
- Cell Line
- Epithelial-Mesenchymal Transition -- drug effects
- Glycogen Synthase Kinase 3 beta -- metabolism
- Humans
- Inhalation Exposure -- adverse effects
- Male
- Mice, Inbred C57BL
- Microscopy, Electron, Scanning
- Microscopy, Electron, Transmission
- Nanotubes, Carbon -- chemistry
- Particle Size
- Proto-Oncogene Proteins c-akt -- metabolism
- Pulmonary Fibrosis -- chemically induced
- Respiratory Mucosa -- drug effects
- Signal Transduction -- drug effects
- Snail Family Transcription Factors -- metabolism
- Surface Properties
- Transforming Growth Factor beta -- agonists
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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