Mitochondrial oxidative phosphorylation controls cancer cell's life and death decisions upon exposure to MAPK inhibitors. [electronic resource]
Producer: 20180111Description: 39473-39485 p. digitalISSN:- 1949-2553
- Animals
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Azetidines -- pharmacology
- Calcium -- chemistry
- Cell Death -- drug effects
- Cell Line, Tumor
- Drug Resistance, Neoplasm -- drug effects
- Endoplasmic Reticulum -- metabolism
- Female
- GTP Phosphohydrolases -- metabolism
- Gene Silencing
- Humans
- Indoles -- pharmacology
- MAP Kinase Signaling System
- Melanoma -- drug therapy
- Mice
- Mice, SCID
- Mitochondria -- metabolism
- Mitochondrial Proteins -- metabolism
- Neoplasms -- enzymology
- Oxidative Phosphorylation
- Piperidines -- pharmacology
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins B-raf -- genetics
- RNA Interference
- Sulfonamides -- pharmacology
- Treatment Outcome
- Vemurafenib
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Publication Type: Journal Article
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