Bone marrow derived mesenchymal stem cells inhibit the proliferative and profibrotic phenotype of hypertrophic scar fibroblasts and keloid fibroblasts through paracrine signaling. [electronic resource]
Producer: 20170502Description: 95-105 p. digitalISSN:- 1873-569X
- Adolescent
- Adult
- Bone Marrow Cells -- cytology
- Cell Proliferation
- Cells, Cultured
- Cicatrix, Hypertrophic -- metabolism
- Collagen Type I -- metabolism
- Connective Tissue Growth Factor -- antagonists & inhibitors
- Culture Media, Conditioned -- pharmacology
- Decorin -- antagonists & inhibitors
- Extracellular Matrix -- metabolism
- Female
- Fibroblasts -- pathology
- Fibronectins -- antagonists & inhibitors
- Humans
- Keloid -- metabolism
- Male
- Mesenchymal Stem Cells -- drug effects
- Middle Aged
- Paracrine Communication
- Plasminogen Activator Inhibitor 1 -- metabolism
- Real-Time Polymerase Chain Reaction
- Skin -- cytology
- Transforming Growth Factor beta1 -- metabolism
- Transforming Growth Factor beta2 -- metabolism
- Transforming Growth Factor beta3 -- metabolism
- Wound Healing -- physiology
- Young Adult
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Publication Type: Journal Article
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