Stilbenoids remodel the DNA methylation patterns in breast cancer cells and inhibit oncogenic NOTCH signaling through epigenetic regulation of MAML2 transcriptional activity. [electronic resource]
Producer: 20170519Description: 656-68 p. digitalISSN:- 1460-2180
- Breast Neoplasms -- drug therapy
- Cell Line, Tumor
- Chromatin -- drug effects
- CpG Islands -- genetics
- DNA (Cytosine-5-)-Methyltransferases -- biosynthesis
- DNA Methylation -- drug effects
- DNA-Binding Proteins -- genetics
- Female
- Gene Expression Regulation, Neoplastic -- drug effects
- Genome, Human
- Humans
- Nuclear Proteins -- genetics
- Organic Cation Transporter 1 -- biosynthesis
- Promoter Regions, Genetic
- Receptors, Notch -- genetics
- Resveratrol
- Signal Transduction -- drug effects
- Stilbenes -- administration & dosage
- Trans-Activators
- Transcription Factors -- genetics
- Transcriptional Activation -- genetics
- DNA Methyltransferase 3B
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Publication Type: Journal Article
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