Combination of carmustine and selenite effectively inhibits tumor growth by targeting androgen receptor, androgen receptor-variants, and Akt in preclinical models: New hope for patients with castration resistant prostate cancer. [electronic resource]
Producer: 20170623Description: 1632-47 p. digitalISSN:- 1097-0215
- Androgen Receptor Antagonists -- administration & dosage
- Animals
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Apoptosis -- drug effects
- Carmustine -- administration & dosage
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Humans
- Male
- Mice
- Mice, Nude
- Molecular Targeted Therapy
- Prostatic Neoplasms, Castration-Resistant -- drug therapy
- Proto-Oncogene Proteins c-akt -- metabolism
- Receptors, Androgen -- metabolism
- Signal Transduction -- drug effects
- Sodium Selenite -- administration & dosage
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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