Allele-specific silencing of EEC p63 mutant R304W restores p63 transcriptional activity. [electronic resource]
Producer: 20171023Description: e2227 p. digitalISSN:- 2041-4889
- Alleles
- Base Sequence
- Cleft Lip -- genetics
- Cleft Palate -- genetics
- Ectodermal Dysplasia -- genetics
- Epithelial Cells -- metabolism
- Gene Silencing
- Genes, Dominant
- Genes, Reporter
- Humans
- Induced Pluripotent Stem Cells -- metabolism
- Luciferases -- genetics
- Molecular Targeted Therapy
- Mutation
- Primary Cell Culture
- RNA, Small Interfering -- genetics
- Syndrome
- Transcription Factors -- antagonists & inhibitors
- Transcription, Genetic
- Tumor Suppressor Proteins -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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