Inhibition of CHK1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells. [electronic resource]
Producer: 20171229Description: 34785-99 p. digitalISSN:- 1949-2553
- Antineoplastic Agents -- pharmacology
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Apoptosis -- drug effects
- Bridged Bicyclo Compounds, Heterocyclic -- pharmacology
- Cell Line, Tumor
- Checkpoint Kinase 1 -- antagonists & inhibitors
- DNA Damage -- drug effects
- Drug Resistance, Neoplasm
- Drug Synergism
- G2 Phase Cell Cycle Checkpoints -- drug effects
- HL-60 Cells
- Humans
- Leukemia, Myeloid, Acute -- drug therapy
- Mitosis -- drug effects
- Myeloid Cell Leukemia Sequence 1 Protein -- metabolism
- Phenylurea Compounds -- pharmacology
- Proto-Oncogene Proteins c-bcl-2 -- antagonists & inhibitors
- Pyrazines -- pharmacology
- Sulfonamides -- pharmacology
- THP-1 Cells
- U937 Cells
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Publication Type: Journal Article
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