Metabolic alterations and drug sensitivity of tyrosine kinase inhibitor resistant leukemia cells with a FLT3/ITD mutation. [electronic resource]
Producer: 20170726Description: 149-57 p. digitalISSN:- 1872-7980
- Angiogenesis Inhibitors -- pharmacology
- Animals
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Deoxyglucose -- pharmacology
- Dose-Response Relationship, Drug
- Drug Resistance, Neoplasm -- drug effects
- G2 Phase Cell Cycle Checkpoints -- drug effects
- Genetic Predisposition to Disease
- Glycolysis -- drug effects
- Humans
- Leukemia, Myeloid, Acute -- drug therapy
- Mice
- Mitochondria -- drug effects
- Mutation
- Niacinamide -- analogs & derivatives
- Phenotype
- Phenylurea Compounds -- pharmacology
- Protein Kinase Inhibitors -- pharmacology
- Pyruvates -- pharmacology
- Signal Transduction -- drug effects
- Sorafenib
- Tandem Repeat Sequences
- Time Factors
- fms-Like Tyrosine Kinase 3 -- antagonists & inhibitors
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Publication Type: Journal Article
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