Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial. [electronic resource]
Producer: 20160801Description: 31-44 p. digitalISSN:- 1474-547X
- Administration, Inhalation
- Adult
- Anti-Asthmatic Agents -- administration & dosage
- Antibodies, Monoclonal -- administration & dosage
- Antibodies, Monoclonal, Humanized
- Asthma -- drug therapy
- Breath Tests
- Budesonide, Formoterol Fumarate Drug Combination -- therapeutic use
- Disease Progression
- Double-Blind Method
- Drug Therapy, Combination
- Female
- Fluticasone-Salmeterol Drug Combination -- therapeutic use
- Forced Expiratory Volume
- Humans
- Injections, Subcutaneous
- Male
- Middle Aged
- Mometasone Furoate, Formoterol Fumarate Drug Combination -- therapeutic use
- Nitric Oxide -- analysis
- Treatment Outcome
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Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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