Polyphenols from Korean prostrate spurge Euphorbia supina induce apoptosis through the Fas-associated extrinsic pathway and activation of ERK in human leukemic U937 cells. [electronic resource]
Producer: 20170313Description: 99-107 p. digitalISSN:- 1791-2431
- Antineoplastic Agents -- isolation & purification
- Apoptosis -- drug effects
- BH3 Interacting Domain Death Agonist Protein -- metabolism
- Baculoviral IAP Repeat-Containing 3 Protein
- Caspase 3 -- metabolism
- Caspase 8 -- metabolism
- Caspase 9 -- metabolism
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cytochromes c -- metabolism
- DNA Fragmentation -- drug effects
- Enzyme Activation -- drug effects
- Euphorbia -- chemistry
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Humans
- Inhibitor of Apoptosis Proteins -- metabolism
- Leukemia -- drug therapy
- MAP Kinase Signaling System -- drug effects
- Membrane Potential, Mitochondrial -- drug effects
- Phosphoinositide-3 Kinase Inhibitors
- Phytochemicals -- pharmacology
- Poly(ADP-ribose) Polymerases -- metabolism
- Polyphenols -- isolation & purification
- Republic of Korea
- U937 Cells
- Ubiquitin-Protein Ligases -- metabolism
- X-Linked Inhibitor of Apoptosis Protein -- metabolism
- bcl-2-Associated X Protein -- biosynthesis
- bcl-Associated Death Protein -- biosynthesis
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Publication Type: Journal Article
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