Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection. [electronic resource]
Producer: 20161014Description: 33 p. digitalISSN:- 1741-7007
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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