Development of Engineered T Cells Expressing a Chimeric CD16-CD3ζ Receptor to Improve the Clinical Efficacy of Mogamulizumab Therapy Against Adult T-Cell Leukemia. [electronic resource]
Producer: 20180112Description: 4405-16 p. digitalISSN:- 1557-3265
- Animals
- Antibodies, Monoclonal, Humanized -- pharmacology
- Antibody-Dependent Cell Cytotoxicity -- immunology
- Antineoplastic Agents, Immunological -- pharmacology
- CD3 Complex -- genetics
- Cell Line, Tumor
- Combined Modality Therapy
- Disease Models, Animal
- Female
- Gene Expression
- Genetic Vectors -- genetics
- Humans
- Immunotherapy, Adoptive
- Killer Cells, Natural -- immunology
- Lentivirus -- genetics
- Leukemia-Lymphoma, Adult T-Cell -- immunology
- Mice
- Receptors, CCR4 -- genetics
- Receptors, IgG -- genetics
- Recombinant Fusion Proteins -- genetics
- T-Cell Antigen Receptor Specificity -- immunology
- T-Lymphocytes -- immunology
- Transduction, Genetic
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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