Altered Bioenergetics in Primary Dermal Fibroblasts from Adult Carriers of the FMR1 Premutation Before the Onset of the Neurodegenerative Disease Fragile X-Associated Tremor/Ataxia Syndrome. [electronic resource]
Producer: 20170925Description: 552-64 p. digitalISSN:- 1473-4230
- Adenosine Triphosphate -- metabolism
- Adolescent
- Adult
- Ataxia -- metabolism
- Biomarkers -- metabolism
- Cells, Cultured
- Child
- Citrate (si)-Synthase -- metabolism
- Dermis -- metabolism
- Endophenotypes -- metabolism
- Fibroblasts -- metabolism
- Fragile X Mental Retardation Protein -- genetics
- Fragile X Syndrome -- metabolism
- Heterozygote
- Humans
- Male
- Middle Aged
- Mitochondria -- metabolism
- Oxidative Stress -- physiology
- Oxygen -- metabolism
- Prodromal Symptoms
- Tremor -- metabolism
- Trinucleotide Repeat Expansion
- Young Adult
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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