Costunolide Induces Apoptosis through Generation of ROS and Activation of P53 in Human Esophageal Cancer Eca-109 Cells. [electronic resource]
Producer: 20170203Description: 462-9 p. digitalISSN:- 1099-0461
- Acetylcysteine -- pharmacology
- Antineoplastic Agents, Phytogenic -- pharmacology
- Apoptosis -- drug effects
- Caspase 3 -- genetics
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Cyclin-Dependent Kinase Inhibitor p21 -- agonists
- Dose-Response Relationship, Drug
- Epithelial Cells -- drug effects
- Esophagus -- drug effects
- Free Radical Scavengers -- pharmacology
- G1 Phase Cell Cycle Checkpoints -- drug effects
- Gene Expression Regulation
- Humans
- Membrane Potential, Mitochondrial -- drug effects
- Mitochondria -- drug effects
- Poly(ADP-ribose) Polymerases -- genetics
- Proto-Oncogene Proteins c-bcl-2 -- antagonists & inhibitors
- Reactive Oxygen Species -- agonists
- Sesquiterpenes -- pharmacology
- Signal Transduction
- Tumor Suppressor Protein p53 -- agonists
- bcl-2-Associated X Protein -- agonists
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Publication Type: Journal Article
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