Lysyl oxidase family activity promotes resistance of pancreatic ductal adenocarcinoma to chemotherapy by limiting the intratumoral anticancer drug distribution. [electronic resource]
Producer: 20171220Description: 32100-12 p. digitalISSN:- 1949-2553
- Amino Acid Oxidoreductases -- genetics
- Animals
- Antimetabolites, Antineoplastic -- pharmacokinetics
- Biomarkers, Tumor -- genetics
- Carcinoma, Pancreatic Ductal -- drug therapy
- Cell Line, Tumor
- Deoxycytidine -- analogs & derivatives
- Diffusion
- Drug Resistance, Neoplasm
- Female
- Fibrillar Collagens -- metabolism
- Gene Expression Regulation, Enzymologic
- Gene Expression Regulation, Neoplastic
- Humans
- Mice, Nude
- Pancreatic Neoplasms -- drug therapy
- Protein-Lysine 6-Oxidase -- genetics
- Tissue Distribution
- Up-Regulation
- Xenograft Model Antitumor Assays
- Gemcitabine
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Publication Type: Journal Article
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