A novel kinase mutation in VEGFR-1 predisposes its αC-helix/activation loop towards allosteric activation: Atomic insights from protein simulation. [electronic resource]
Producer: 20170726Description: 1287-93 p. digitalISSN:- 1476-5438
- Allosteric Regulation
- Allosteric Site
- Colorectal Neoplasms -- genetics
- Female
- Gene Deletion
- Humans
- Male
- Molecular Dynamics Simulation
- Mutation, Missense
- Phosphorylation
- Polymorphism, Single Nucleotide
- Protein Conformation, alpha-Helical
- Protein Processing, Post-Translational
- Vascular Endothelial Growth Factor Receptor-1 -- chemistry
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Publication Type: Journal Article
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