ASC-J9(®), and not Casodex or Enzalutamide, suppresses prostate cancer stem/progenitor cell invasion via altering the EZH2-STAT3 signals. [electronic resource]
Producer: 20170206Description: 377-86 p. digitalISSN:- 1872-7980
- Androgen Antagonists -- pharmacology
- Anilides -- pharmacology
- Animals
- Antineoplastic Agents, Hormonal -- pharmacology
- Benzamides
- Cell Line, Tumor
- Cell Movement -- drug effects
- Curcumin -- analogs & derivatives
- Enhancer of Zeste Homolog 2 Protein -- genetics
- Humans
- Male
- Mice, Nude
- Neoplasm Invasiveness
- Neoplastic Stem Cells -- drug effects
- Nitriles -- pharmacology
- Phenylthiohydantoin -- analogs & derivatives
- Prostatic Neoplasms -- drug therapy
- Proto-Oncogene Proteins c-akt -- metabolism
- STAT3 Transcription Factor -- genetics
- Side-Population Cells -- drug effects
- Signal Transduction -- drug effects
- Tosyl Compounds -- pharmacology
- Xenograft Model Antitumor Assays
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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