Structural basis for specific inhibition of Autotaxin by a DNA aptamer. [electronic resource]
Producer: 20170629Description: 395-401 p. digitalISSN:- 1545-9985
- Animals
- Aptamers, Nucleotide -- chemistry
- Base Sequence
- Binding Sites
- Crystallography, X-Ray
- HEK293 Cells
- Humans
- Hydrogen Bonding
- Hydrophobic and Hydrophilic Interactions
- Inverted Repeat Sequences
- Male
- Mice, Inbred C57BL
- Models, Molecular
- Phosphodiesterase Inhibitors -- chemistry
- Phosphoric Diester Hydrolases -- chemistry
- Protein Binding
- Protein Conformation, alpha-Helical
- Protein Domains
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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