Long-Term Exposure of Pancreatic β-Cells to Palmitate Results in SREBP-1C-Dependent Decreases in GLP-1 Receptor Signaling via CREB and AKT and Insulin Secretory Response. [electronic resource]
Producer: 20170605Description: 2243-58 p. digitalISSN:- 1945-7170
- Animals
- Cell Line
- Cyclic AMP Response Element-Binding Protein -- metabolism
- Exenatide
- Glucagon-Like Peptide-1 Receptor -- metabolism
- Humans
- Insulin -- metabolism
- Insulin-Secreting Cells -- drug effects
- Islets of Langerhans -- drug effects
- Male
- Mice
- Mice, Inbred C57BL
- Palmitates -- pharmacology
- Peptides -- pharmacology
- Proto-Oncogene Proteins c-akt -- metabolism
- Rats
- Signal Transduction -- drug effects
- Sterol Regulatory Element Binding Protein 1 -- metabolism
- Venoms -- pharmacology
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Publication Type: Journal Article
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