Investigation of the effect of food and omeprazole on the relative bioavailability of a single oral dose of 240 mg faldaprevir, a selective inhibitor of HCV NS3/4 protease, in an open-label, randomized, three-way cross-over trial in healthy participants. [electronic resource]
Producer: 20170509Description: 459-66 p. digitalISSN:- 2042-7158
- Administration, Oral
- Adult
- Aminoisobutyric Acids
- Antiviral Agents -- administration & dosage
- Area Under Curve
- Biological Availability
- Cross-Over Studies
- Female
- Food-Drug Interactions
- Healthy Volunteers
- Hepacivirus -- drug effects
- Humans
- Leucine -- analogs & derivatives
- Male
- Metabolic Clearance Rate
- Middle Aged
- Oligopeptides -- administration & dosage
- Omeprazole -- administration & dosage
- Proline -- analogs & derivatives
- Protease Inhibitors -- administration & dosage
- Proton Pump Inhibitors -- administration & dosage
- Quinolines
- Risk Factors
- Thiazoles -- administration & dosage
- Viral Nonstructural Proteins -- antagonists & inhibitors
- Young Adult
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Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial
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