GATA3 mRNA expression, but not mutation, associates with longer progression-free survival in ER-positive breast cancer patients treated with first-line tamoxifen for recurrent disease. [electronic resource]
Producer: 20170213Description: 104-9 p. digitalISSN:- 1872-7980
- Antineoplastic Agents, Hormonal -- adverse effects
- Biomarkers, Tumor -- genetics
- Breast Neoplasms -- drug therapy
- Chi-Square Distribution
- DNA Mutational Analysis
- Disease-Free Survival
- Female
- GATA3 Transcription Factor -- genetics
- Gene Expression Regulation, Neoplastic
- Humans
- Kaplan-Meier Estimate
- Logistic Models
- Multivariate Analysis
- Mutation
- Neoplasm Recurrence, Local
- Odds Ratio
- Proportional Hazards Models
- RNA, Messenger -- genetics
- Receptors, Estrogen -- antagonists & inhibitors
- Retrospective Studies
- Risk Factors
- Selective Estrogen Receptor Modulators -- adverse effects
- Tamoxifen -- adverse effects
- Time Factors
- Treatment Outcome
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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