Design, synthesis and biological evaluation of 6-substituted pyrrolo[2,3-d]pyrimidines as dual inhibitors of TS and AICARFTase and as potential antitumor agents. [electronic resource]
Producer: 20170109Description: 245-56 p. digitalISSN:- 1768-3254
- Antineoplastic Agents -- chemical synthesis
- Cell Line, Tumor
- Drug Design
- Enzyme Inhibitors -- chemical synthesis
- Humans
- Models, Molecular
- Phosphoribosylaminoimidazolecarboxamide Formyltransferase -- antagonists & inhibitors
- Pyrimidines -- chemical synthesis
- Pyrroles -- chemistry
- Thymidylate Synthase -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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