An integrin beta4-EGFR unit promotes hepatocellular carcinoma lung metastases by enhancing anchorage independence through activation of FAK-AKT pathway. [electronic resource]
Producer: 20170213Description: 188-96 p. digitalISSN:- 1872-7980
- Adult
- Aged
- Animals
- Anoikis
- Carcinoma, Hepatocellular -- enzymology
- Cell Proliferation
- Enzyme Activation
- ErbB Receptors -- metabolism
- Female
- Focal Adhesion Kinase 1 -- metabolism
- Gene Expression Regulation, Neoplastic
- Hep G2 Cells
- Heterografts
- Humans
- Integrin beta4 -- genetics
- Liver Neoplasms -- enzymology
- Lung Neoplasms -- enzymology
- Male
- Mice, Inbred BALB C
- Mice, Nude
- Middle Aged
- Neoplasm Transplantation
- Proto-Oncogene Proteins c-akt -- genetics
- RNA Interference
- Signal Transduction
- Transfection
- Tumor Burden
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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