Rhapontigenin inhibits TGF-β-mediated epithelial‑mesenchymal transition via the PI3K/AKT/mTOR pathway and is not associated with HIF-1α degradation. [electronic resource]
Producer: 20161227Description: 2887-95 p. digitalISSN:- 1791-2431
- Antineoplastic Agents -- pharmacology
- Drug Screening Assays, Antitumor
- Epithelial-Mesenchymal Transition
- HeLa Cells
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit -- metabolism
- Phosphatidylinositol 3-Kinases -- metabolism
- Proteasome Endopeptidase Complex -- metabolism
- Proteolysis
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction
- Snail Family Transcription Factors -- metabolism
- Stilbenes -- pharmacology
- TOR Serine-Threonine Kinases -- metabolism
- Transforming Growth Factor beta1 -- physiology
- Ubiquitination
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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