Synthesis, in vitro and in vivo evaluation of novel substituted N-(4-(2-(4-benzylpiperazin-1-yl)ethoxy)phenyl)-N-methyl-quinazolin-4-amines as potent antitumor agents. [electronic resource]
Producer: 20161213Description: 1931-5 p. digitalISSN:- 1464-3405
- Animals
- Antineoplastic Agents -- chemical synthesis
- Apoptosis -- drug effects
- Cell Cycle Checkpoints -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Humans
- Liver Neoplasms, Experimental -- drug therapy
- Mice
- Mice, Nude
- Molecular Docking Simulation
- Molecular Structure
- Piperazines -- chemical synthesis
- Quinazolines -- chemical synthesis
- Structure-Activity Relationship
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Publication Type: Journal Article
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