Diosgenin induces ROS-dependent autophagy and cytotoxicity via mTOR signaling pathway in chronic myeloid leukemia cells. [electronic resource]
Producer: 20160921Description: 243-52 p. digitalISSN:- 1618-095X
- Animals
- Antineoplastic Agents, Phytogenic -- pharmacology
- Apoptosis -- drug effects
- Autophagy -- drug effects
- Cell Line, Tumor
- Diosgenin -- pharmacology
- Humans
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive -- pathology
- Mice
- Reactive Oxygen Species -- metabolism
- Signal Transduction -- drug effects
- TOR Serine-Threonine Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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