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  2. Details for: Optimisation of a 5-[3-phenyl-(2-cyclic-ether)-methyl-ether]-4-aminopyrrolopyrimidine series of IGF-1R inhibitors.
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Optimisation of a 5-[3-phenyl-(2-cyclic-ether)-methyl-ether]-4-aminopyrrolopyrimidine series of IGF-1R inhibitors. [electronic resource]

By:
  • Fairhurst, Robin A
Contributor(s):
  • Marsilje, Thomas H
  • Stutz, Stefan
  • Boos, Andreas
  • Niklaus, Michel
  • Chen, Bei
  • Jiang, Songchun
  • Lu, Wenshuo
  • Furet, Pascal
  • McCarthy, Clive
  • Stauffer, Frédéric
  • Guagnano, Vito
  • Vaupel, Andrea
  • Michellys, Pierre-Yves
  • Schnell, Christian
  • Jeay, Sébastien
Producer: 20161213Description: 2057-64 p. digitalISSN:
  • 1464-3405
Subject(s):
  • Animals
  • Antineoplastic Agents -- chemical synthesis
  • Cell Proliferation -- drug effects
  • Dose-Response Relationship, Drug
  • Humans
  • Imidazoles -- chemical synthesis
  • Mice
  • Mice, Nude
  • Molecular Structure
  • NIH 3T3 Cells
  • Neoplasms, Experimental -- drug therapy
  • Protein Kinase Inhibitors -- chemical synthesis
  • Pyrazines -- chemical synthesis
  • Pyrimidines -- chemical synthesis
  • Pyrroles -- chemical synthesis
  • Receptor, IGF Type 1 -- antagonists & inhibitors
  • Structure-Activity Relationship
  • Xenograft Model Antitumor Assays
Online resources:
  • Available from publisher's website
In: Bioorganic & medicinal chemistry letters vol. 26
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Publication Type: Journal Article

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Optimisation of a 5-[3-phenyl-(2-cyclic-ether)-methyl-ether]-4-aminopyrrolopyrimidine series of IGF-1R inhibitors.

APA

Fairhurst R. A., Marsilje T. H., Stutz S., Boos A., Niklaus M., Chen B., Jiang S., Lu W., Furet P., McCarthy C., Stauffer F., Guagnano V., Vaupel A., Michellys P., Schnell C. & Jeay S. (20161213). Optimisation of a 5-[3-phenyl-(2-cyclic-ether)-methyl-ether]-4-aminopyrrolopyrimidine series of IGF-1R inhibitors. : Bioorganic & medicinal chemistry letters.

Chicago

Fairhurst Robin A, Marsilje Thomas H, Stutz Stefan, Boos Andreas, Niklaus Michel, Chen Bei, Jiang Songchun, Lu Wenshuo, Furet Pascal, McCarthy Clive, Stauffer Frédéric, Guagnano Vito, Vaupel Andrea, Michellys Pierre-Yves, Schnell Christian and Jeay Sébastien. 20161213. Optimisation of a 5-[3-phenyl-(2-cyclic-ether)-methyl-ether]-4-aminopyrrolopyrimidine series of IGF-1R inhibitors. : Bioorganic & medicinal chemistry letters.

Harvard

Fairhurst R. A., Marsilje T. H., Stutz S., Boos A., Niklaus M., Chen B., Jiang S., Lu W., Furet P., McCarthy C., Stauffer F., Guagnano V., Vaupel A., Michellys P., Schnell C. and Jeay S. (20161213). Optimisation of a 5-[3-phenyl-(2-cyclic-ether)-methyl-ether]-4-aminopyrrolopyrimidine series of IGF-1R inhibitors. : Bioorganic & medicinal chemistry letters.

MLA

Fairhurst Robin A, Marsilje Thomas H, Stutz Stefan, Boos Andreas, Niklaus Michel, Chen Bei, Jiang Songchun, Lu Wenshuo, Furet Pascal, McCarthy Clive, Stauffer Frédéric, Guagnano Vito, Vaupel Andrea, Michellys Pierre-Yves, Schnell Christian and Jeay Sébastien. Optimisation of a 5-[3-phenyl-(2-cyclic-ether)-methyl-ether]-4-aminopyrrolopyrimidine series of IGF-1R inhibitors. : Bioorganic & medicinal chemistry letters. 20161213.

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