Synthesis, structural characterization, docking, lipophilicity and cytotoxicity of 1-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]-3-alkyl carbamates, novel acetylcholinesterase and butyrylcholinesterase pseudo-irreversible inhibitors. [electronic resource]
Producer: 20161108Description: 1560-72 p. digitalISSN:- 1464-3391
- Acetylcholinesterase -- metabolism
- Benzothiazoles -- chemical synthesis
- Butyrylcholinesterase -- metabolism
- Carbamates -- chemical synthesis
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Cholinesterase Inhibitors -- chemical synthesis
- Dose-Response Relationship, Drug
- Humans
- Hydrophobic and Hydrophilic Interactions
- Jurkat Cells
- Molecular Docking Simulation
- Molecular Structure
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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