TNF-α is upregulated in T2DM patients with fracture and promotes the apoptosis of osteoblast cells in vitro in the presence of high glucose. [electronic resource]
Producer: 20161229Description: 35-42 p. digitalISSN:- 1096-0023
- Aged
- Apoptosis -- genetics
- Bone and Bones -- pathology
- C-Reactive Protein -- genetics
- Caspase 3 -- genetics
- Cell Line, Tumor
- Cell Survival
- Chemokines -- blood
- Cytochromes c -- genetics
- Cytokines -- blood
- Diabetes Mellitus, Type 2 -- complications
- Female
- Fracture Healing -- drug effects
- Fractures, Bone -- immunology
- Glucose -- pharmacology
- Humans
- Interleukin-1beta -- blood
- Male
- Middle Aged
- Osteoblasts -- drug effects
- Tumor Necrosis Factor-alpha -- blood
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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