Overexpression of Homer1a in the basal and lateral amygdala impairs fear conditioning and induces an autism-like social impairment. [electronic resource]
Producer: 20160419Description: 16 p. digitalISSN:- 2040-2392
- Acoustic Stimulation
- Animals
- Autism Spectrum Disorder -- etiology
- Basolateral Nuclear Complex -- drug effects
- Carrier Proteins -- biosynthesis
- Conditioning, Classical -- physiology
- Disease Models, Animal
- Electroshock
- Exploratory Behavior -- drug effects
- Fear -- drug effects
- Female
- Freezing Reaction, Cataleptic
- Gene Expression Regulation -- drug effects
- Genetic Vectors -- administration & dosage
- Homer Scaffolding Proteins
- Nerve Tissue Proteins -- biosynthesis
- Pregnancy
- Prenatal Exposure Delayed Effects
- RNA, Messenger -- biosynthesis
- Rats
- Recombinant Fusion Proteins -- biosynthesis
- Social Behavior
- Teratogens -- pharmacology
- Transduction, Genetic
- Valproic Acid -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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